许多真菌感染都能形成肉芽肿，免疫缺陷病人免疫反应很差,肉芽肿很少形成，或根本不会形成。肝脏标本中黄褐色部分为肉芽肿，该病人患组织胞浆菌病。

荚膜组织胞浆菌: 肝脏肉芽肿（大体） 　显微镜　PAS染色

Many fungal infections can produce a granulomatous pattern. In immunocompromised hosts, the immune response is often poor, so granulomas are poorly formed, if at all. This portion of liver demonstrates some pinpoint yellow-tan granulomas in a patient with disseminated histoplasmosis.