左上方是残留的食管鳞状上皮，已被食管中段鳞状细胞癌破坏。左侧可见肿瘤细胞巢正向下浸润突破黏膜下层。食管癌经常浸润破坏周围组织，使得外科手术切除很困难。
At the upper left is a remnant of squamous esophageal mucosa that has been undermined by an infiltrating squamous cell carcinoma of the mid-esophagus. Solid nests of neoplastic cells are infiltrating down through the submucosa at the right. Esophageal cancers often spread to surrounding structures, making surgical removal difficult.
