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HE染色与免疫过氧化物酶染色显示Lewy小体(高倍镜)

弥漫性Lewy小体病病人,左边HE染色显示大脑皮质神经元中的圆形粉红色胞质Lewy小体,Lewy小体可能是痴呆的原因。Parkinson病黑质中也能见到Lewy小体。右边采用泛素免疫过氧化物酶染色,Lewy小体清晰可见。

At the left, an H and E stain demonstrates a rounded pink cytoplasmic Lewy body in a neuron of the cerebral cortex from a patient with diffuse Lewy body disease, which can be a cause for dementia. Lewy bodies can also be seen in substantia nigra with Parkinson's disease. An immunoperoxidase stain for ubiquitin, seen at the right, helps demonstrate the Lewy bodies more readily.

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