图示乳腺导管内癌典型的筛孔状结构。导管内的肿瘤上皮细胞表现为淡染和多型现象，但是他们有边缘锐利的孔像被切饼机切过一样。 The classic cribriform pattern of intraductal carcinoma of the breast is shown here. The neoplastic epithelial cells within the duct show minimal hyperchromatism and pleomorphism, but they have holes with sharp margins as though punched out by a cookie cutter.