弥散性血管内凝血(DIC)时凝血系统激活后肾小球毛细血管袢中可见纤维素性微血栓，纤维素染色呈现高亮度红色(箭头所指)。实验室检查发现血小板减少、纤维蛋白原减少、凝血酶原时间延长、部分凝血活酶时间延长、D-二聚体升高。由凝血因子消耗、纤维蛋白降解产物(FDP)的生成 、血小板消耗所致。
弥散性血管内凝血(DIC)：肺内纤维素性微血栓(高倍镜)
Small fibrin thrombi from widespread activation of the coagulation system with disseminated intravascular coagulopathy (DIC) can be seen in capillary loops in this glomerulus, highlighted by a fibrin stain. Laboratory findings with DIC include decreased platelets, diminished fibrinogen, prolonged prothrombin time, elevated partial thromboplastin time, and elevated D-dimer. Consumption of coagulation factors with generation of fibrin split products, along with platelet consumption, leads to these findings.